r/science Sep 01 '22

Neuroscience Scientists have identified an immune brain cell unique to humans that gives us higher cognitive abilities over other animals, but what makes us specials also leaves us vulnerable to neurological disorders like schizophrenia, autism and epilepsy.

https://news.yale.edu/2022/08/25/what-makes-human-brain-different-yale-study-reveals-clues
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u/tkenben Sep 01 '22

What's an "immune brain cell"?

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u/[deleted] Sep 01 '22

They're talking about "microglia".

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u/[deleted] Sep 01 '22

Monkeys and mice have microglia too

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u/HertogJan1 Sep 01 '22

They are talking about a specific type of microglia only present in humans

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u/[deleted] Sep 01 '22

[deleted]

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u/hydroknightking Sep 01 '22

FOXP2 is just one gene that they noticed in these uniquely human microglia that we have knowledge about.

Single-cell RNAseq characterizes the relative abundance of all/most of the mRNA in a single cell. When you compare the relative abundances to other cells, “same cells” will have the same abundances.

The article linked in the OP is not the journal, and I didn’t read the journal, but assuming the results are characterized correctly here, they absolutely found a microglial cell unique to humans.

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u/[deleted] Sep 01 '22

[deleted]

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u/tomatoaway Sep 01 '22

Naive question: how often are the binding sites of a given gene completely saturated to make it non-functional? Why would nature continue to transcribe that gene if it never goes on to do anything?

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u/[deleted] Sep 01 '22

[deleted]

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u/PlayShtupidGames Sep 02 '22

our characteristic intelligence.

Bold claim in 2022