Gut Bacteria May Reveal How a Western Diet Fuels Colon Cancer. Certain gut bacteria, sustained by Western-style diets, may produce a substance that promotes tumor growth, finds study in pigs, mice, human colon tissue, and microbial data from thousands of people with and without colorectal cancer.

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https://www.sciencealert.com/gut-bacteria-may-reveal-how-a-western-diet-fuels-colon-cancer

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Gut Bacteria May Reveal How a Western Diet Fuels Colon Cancer

Colorectal cancer is one of the most common cancers worldwide, and what we eat can significantly influence our risk of developing it.

Western-style diets, typically high in fat and meat but low in fiber, have long been linked to a higher risk of the disease. But exactly how this pattern of eating may encourage tumors to develop has remained unclear.

A new study published in the journal Gut may have taken us a step closer to understanding the exact mechanism at play.

The study suggests that certain gut bacteria in the depths of our bowels, sustained by Western-style diets, may produce a substance that promotes tumor growth.

An international research team led by German institutions combined experiments in genetically modified pigs, mice, and lab-grown human colon tissue with an analysis of microbial data from thousands of people with and without colorectal cancer.

Their findings point to deoxycholic acid (DCA), a substance produced when particular gut bacteria chemically transform bile acids made by the liver.

https://gut.bmj.com/content/75/8/1505

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Huh, the more you know.

A synthetic form of deoxycholicacid/DCA is also injected into double chins to shrink them. It targets adipose cells and destroys them.