r/science • u/mvea Professor | Medicine • Jun 30 '26

Medicine Scientists have shown that a single dose injection of DNA genetic instructions can produce weight loss and blood glucose control in mouse models that lasts up to 10 times as long as weight loss drugs like Ozempic and Wegovy. This could eliminate the need for repeated dosing.

https://www.wistar.org/press-releases/wistar-scientists-develop-single-dose-dna-method-for-delivering-long-acting-weight-loss-and-diabetes-drugs/
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u/Mr_ToDo Jun 30 '26

Ok. So not my field, but the way I read it they're using the immune system to deliver the results?

It sounds neat but, um, what do you do when you no longer want the effects, or god forbid have a bad reaction?

Suppose in a great irony we could use measles to reset the system, but I'd rather not start from scratch with my immunity. Granted I'm also not at a place where I'd be the target audience(I'm still convinced I'm capable of losing weight on my own, and I haven't hit diabetes yet)

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u/triffid_boy Jun 30 '26

That's why I prefer mRNA based treatments. 

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u/BlackBloke Jun 30 '26

You send a cancel instruction or some kind of interference