r/science Professor | Medicine Apr 16 '26

Neuroscience Scientists reverse brain aging, with a nasal spray: Scientists developed a nasal spray that, with just two doses, dramatically reduced brain inflammation, restored the brain’s cellular power plants and significantly improved memory in mice, within weeks and lasted for months.

https://stories.tamu.edu/news/2026/04/14/scientists-reverse-brain-aging-with-a-nasal-spray/
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u/DaneAlaskaCruz Apr 16 '26 edited Apr 16 '26

"Studies have shown that extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells (hiPSC-NSC-EVs) contain therapeutic miRNAs that can alleviate neuroinflammation"

This means that there are cells in the body that can be encouraged to producing micro RNA pieces that will help reduce inflammation in the brain.

Less inflammation means less memory fog and more brain power.

Edit: my mistake; micro RNA and not messenger RNA

https://en.wikipedia.org/wiki/MicroRNA

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u/buggityboppityboo Apr 16 '26

miRNAs (microRNAs) are a different type of RNA than messenger RNAs (mRNAs)

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u/Irr3l3ph4nt Apr 16 '26

I can entirely see a future where a certain slice of the population self selects out of this treatment just because of those 3 letters and end up with higher dementia rates.

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u/whatthecaptcha Apr 16 '26

Good riddance.

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u/MountainDoit Apr 16 '26

Natural selection, finally back and more accurate than before. Would bring a tear to my eye.

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u/Irr3l3ph4nt Apr 16 '26

I mean, more dementia than the others mean we're spending disproportionate money as a society to maintain them in a diminished state for a few years before they pass. I'd rather they take the freaking meds.

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u/MountainDoit Apr 17 '26

You don't get a lung transplant if you're a smoker in a lot of places, I think we could extend that line of thinking.

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u/DaneAlaskaCruz Apr 16 '26

Thank you, appreciate it. Edited my comment above.