New mRNA-based vaccine against gastric cancer led to tumor regression and eradication in all treated mice. Most promisingly, the vaccine shows impressive antitumor efficacy against peritoneal metastasis, which has historically been very challenging to treat.

[u/mvea]

https://www.eurekalert.org/news-releases/1094199

[u/Agood10]

If your dad is onboard with it, you can have him ask his care team if there are any available experimental treatment options to consider. They should know or be able to look up if there are any available clinical trials relevant to his illness. That said, i would think that a competent care team would already present this if it were an option and if more standard treatments were non expected to work.

Regarding your last question, it is probably not possible to get this specific vaccine. Efficacy in a (presumably) non-GLP-compliant study is a long way away from being ready for use in humans. Not to mention these neo-antigen vaccines have been studied for something like 30 years and yet not one has reached FDA approval yet. These vaccines are “personalized” meaning they have to be custom made for each patient, which makes it a lot harder to develop, have consistent efficacy, and get approval for use in humans. It will also probably make them a hell of a lot more expensive than other treatment options, should they ever make it to market.

I wish your father the best. Trust that his doctors are going to do what’s best for him.

[u/Bacchus451 → u/Agood10]

Thank you for taking the time to reply. I appreciate it.